problem with missile lock

I'm sorry with noob question but I finally tried EE twice this week with friends (Just 2 years that I was waiting for this moment). I love this game.
I translate some scenarios and we loved experience.
I don't understand why sometimes is difficult to lock ships with homing or nuke? Even being at a good distance?
is it due to some protection characteristics of ships?

Please look picture :

image

Thanks

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